The purpose of this research is to investigate the factors affecting the formation of leading schools, so that it can be used in Iran's education. For this purpose, first, according to the research background and theoretical foundations, a conceptual framework was presented in the field of the components of an efficient and progressive school. Due to the nature of the subject, this research is an applied and developmental research and its method is of a mixed type, and includes quantitative and qualitative methods. According to the obtained information, the statistical population is about 3000 people. The sample size is estimated to be 344 people using Morgan's table. Stratified sampling method was used for sampling in this research, and 84 managers and 260 teachers participated in this study. The tool of this research is a researcher-made questionnaire. To analyze the data and answer the research questions, the correlation coefficient test and factor analysis were used. The results of the research showed that the components of management and leadership, research factors, educational factors, human resources, budget and infrastructure, technology and equipment are the main components of the formation of leading schools, and the component of educational factors has the largest contribution.

Background and Objective: Bordetella pertussis is a gram-negative cocobacilli bacterium and etiologic agent of whooping cough that in recent years, the number of its cases is on the rise. The ability of biofilm production helps this bacterium in interference with host immune system, severity of illness and antibiotic sensitivity. Thus, due to the importance of this factor, in this investigation, we tested the ability of Bordetella pertussis isolates in biofilm formation.Materials and Methods: Nasopharyngeal samples were collected from persons who suspected whooping cough from throughout of Iran from 2014 to 2016 and were transferred to pertussis reference laboratory in Pasteur Institute of Iran. The bacterium in question was isolated by culture so that finally we had 20 positive samples. At the end, we performed in vitro biofilm formation test for isolated strains.Results: All of the 20 clinical samples of Bordetella pertussis which in this study were examined could form biofilm and their final OD became between 0.606 and 1.212, the power of the biofilm made by them was intermediate. Conclusion: Findings of this study was similar to researches conducted by other researchers, which showed the ability of the strains of Bordetella pertussis to form biofilm and to create adverse effects on the host for example antibiotic resistance, illness severity, and so on. Thus, considering the importance of this issue, more and broader researches are needed in this area.

A B S T R A C TThe morphology of each region is related to its landforms, the morphology of flat areas is related to inselbergs. The presence of inselbergs in desert and dry areas gives a special appearance to the morphology of these areas. The study of these landforms and the effective factors in their formation is considered a necessity in terms of regional development. According to the studies, various factors play a role in the formation of inselbergs, and the role of lithology seems to be more prominent. In this research, which was conducted with the method of field and library studies, we identified 18 inselbergs in Safi Abad plain and by studying them, we came to the conclusion that the inselbergs of this plain are mainly formed in sedimentary rocks such as limestone, conglomerate and sandstone. Among the geological formations, the largest and most diverse inselbergs in the Safiabad plain are formed in the mass conglomerate formation with good hardening because this formation is the most widespread in this plain. But the most typical inselbergs of this plain are formed in thick layered limestone. Because this formation is more resistant to erosion. Lar formations including Limestone and Thick Limestone’s to Mass Dolomite and Delichai formations have also played an important role in the formation of inselbergs in this plain. Although the extent of these formations is not significant, but due to their significant resistance to erosion and being far from these processes, they have caused the formation of evolved inselbergs in this plainExtended AbstractIntroductionInselbergs are ridges with a height of less than 500 meters formed with a steep slope in the plains. Their resistance to erosion has caused them to be considered capable players in the morphology of arid and semi-arid regions. Due to their uniqueness in desert areas, these areas are of interest to tourists, and the economic situation of these areas can be improved by attracting tourists. The prominence of inselbergs in desert areas has caused researchers to pay attention to their studies, the most important of which are the studies of Pye in Kenya (1984), Nenonen in Finland (2018), Luiza in Brazil (2021), Laetitia in Africa (2019), and Mashaal in Egypt (2020). Although the conditions for inselberg formation are available in some areas of Iran, and these landforms have given a particular face to the morphology of this country, no significant study has been done on them so far. This research attempts to investigate the role of lithology in inselberg formation in Safi Abad Plain by using library and field studies. MethodologySafi Abad plain in the northeast of Iran and North Khorasan province and in terms of geographical coordinates between 36-˚ 48-05 to 36-22-55˚ North and 37-57˚ East to 36-˚ 37-08 It is located at 57-58-11 east. Field and library studies were used to study the inselbergs of this plain. The entire region was surveyed in 2 years in the field studies, and 18 inselbergs were identified. Then, the location and extent of their expansion were determined. In the morphometry that was done as a survey, the minimum height, length-to-width ratio of inselbergs, and their distance from each other were measured with GPS. The study of the concepts, definitions, and effective processes in inselberg formation was done with the library method. The maps of this research were drawn with Adobe Illustrator software. Results and discussionInselbergs are diverse in terms of morphology; in the studied area, 18 inselbergs were identified, most of which are mixed. Most of them are rocky and have less vegetation. Regarding lithology, inselbergs are particular forms of igneous and metamorphic rocks, but some are also formed in other rocks. Although lithology plays an essential role in inselberg morphology, it cannot be claimed that inselbergs formed in the same formation have the same shape. Although the dominant lithology of the Safi Abad plain is formed from sedimentary rocks, due to the different resistance of its formations, the height, shape, and slope of the inselbergs of this plain are different in different parts of the region. The difference in these characteristics has caused the different shapes of the land in this plain. According to the studies of the most resistant formations of Safi Abad plain against erosion, limestone is a thick layer of chert mass formed due to the resistance against the erosion of the complete inselbergs.After this formation, the Lar formation consists of fine-grained uniform dolomitic limestone with thick to massive layering, which is more resistant; that is why many inselbergs in the region have formed in it. The third formation in terms of resistance is the Apsin-Albin unit, which includes orbitolinate limestone and thick limes to a mass of dolomite. Although this unit has a small area, its inselbergs are closer to typical inselbergs. In terms of area, most of the area is composed of mass conglomerates with good hardening. Due to the different effects of this formation from different processes, its inselbergs do not have the same morphology. The inselbergs formed in this formation are in the middle part of the high area, low in the southern part, incomplete in the western part, and incomplete mushrooms in the path of the Gerati River. After this formation, gray shales are the most resistant to erosion. This formation, which belongs to the Jurassic period, has formed a large part of the northeastern inselbergs. The alternation of limestone and marl in the Delichai formations in the middle part of the region provides the basis for the formation of mushroom-shaped inselbergs in the future. ConclusionSafiabad Plain is in the northeast of Iran, and in terms of geomorphological units, it is part of central Iran. Inselbergs form part of the morphology of this plain. In this study, 18 inselbergs were identified in this plain, and their detailed study showed that their primary skeleton was established by tectonic activities in the Devonian to Miocene period with the formation of Posht Bahram mountains. It was formed when the tectonic activities calmed down and in opposition to the lithology and erosion of the inselbergs of this plain. In terms of lithology, the well-hardened conglomerate formation covers nearly 47% of this plain, and due to its large size and different distances from erosion processes, various inselbergs have been formed in it. The southern inselbergs formed in this formation have a regular shape due to wind and blue erosion. In contrast, the middle inselbergs have an incomplete shape due to the distance from higher erosion, and the western inselbergs have an incomplete shape due to the superiority of blue erosion. Another formation that plays a vital role in this field is Lar Mei formation. Although this is the second formation in terms of size and strength, many inselbergs have formed in it. The Shemshak formation is placed after the Lar formation in terms of resistance. This formation has caused the formation of chain inselbergs in the northeast of the region. The most typical inselbergs of the region are observed in the thick layered limestones of the formation (Maastrichtian). Also, this research found that inselbergs may be formed in all flat areas of the world and even in sedimentary formations. However, the inselbergs formed are far from those formed in tropical regions' igneous and metamorphic formations. FundingThere is no funding support. Authors’ ContributionThe authors contributed equally to the conceptualization and writing of the article. All of the authors approthe contenttent of the manuscript and agreed on all aspects of the work declaration of competing interest none. Conflict of InterestThe authors declared no conflict of interest. Acknowledgments We are grateful to all the scientific consultants of this paper.

One of the main sources for attaining religious teachings is the tradition of Prophet Mohammad and the Infallible Imams, without which it is not possible to attain Islam’s religious teachings. Furthermore, considering the comprehensiveness of Islam in the guidance of human beings, the inference of religious teachings related to human sciences is an inevitable necessity, which has become the concern of researchers titled "Islamization of human sciences". Using a descriptive-analytical method, this article studies the role of the tradition of Prophet Mohammad and the Infallible Imams in the Islamization of human sciences, with an emphasis on the thoughts of the great Islamic scholar, Allameh Misbah Yazdi. Although all Muslims believe Islamic tradition is a source for obtaining religious teachings, but the reasons they present for its authenticity and the scope of this tradition are seriously debatable; in addition, methodologically, documenting the Islamization of human sciences by Islamic tradition has its own difficulties, pointed in this article.

Background: The importance of dose in prostate radiotherapy is well known, and the dosimetric effects of radiotherapy in node-positive or node-negative patients with prostate cancer have become an important issue. Materials and Methods: Helical tomotherapy (TH) plans of 19 pelvic node-positive [THpn(+) plan] or node-negative [THpn(-) plan] patients with prostate cancer were retrospectively created in our clinic. In these plans, the beam angle was set to cover the planning target volume (PTV) of prostate cancer and minimize the dose to the organs at risk, including the bladder, rectum, femoral head, and bowel. Results: There were no differences in the conformity index, Dmax, Dmean, and homogeneity index of PTV between the THpn (+) and THpn (-) plans (p>0. 05). However, V95 in the THpn (+) plan was lower than that in the THpn (-) plan (p=0. 017). Moreover, Dmax, V75, V70, V65, V60, V50, V40, V30, and V20 for the rectum were not significantly different between the two plans (p>0. 05), whereas Dmean was significantly different (p=0. 025). Dmax, V70, V65, and V60 for the bladder were not significantly different between the two plans (p>0. 05), whereas V55, V50, V40, and V30 were significantly different (p<0. 05). Finally, Dmax and V50 for the femoral head and bowel were significantly different between the two plans (p<0. 05). Conclusion: The THpn (+)] and [THpn(-) plans achieved acceptable target dose coverage in prostate radiotherapy.